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Journal article
111. Germanyl triazoles as a platform for CuAAC diversification and chemoselective orthogonal cross-coupling
Published on
5/12/2024
Research area:
Click Chemistry
Journal article
110. Assessing the Manufacturability and Critical Quality Attribute Profiles of Anti-IL-8 Immunoglobulin G Mutant Variants
Published on
7/11/2024
Research area:
Bioconjugation chemistry
Research area:
Other
Research area:
Medicinal Chemistry
Journal article
109. Core Modifications of GSK3335103 toward Orally Bioavailable αvβ6 Inhibitors with Improved Synthetic Tractability
Published on
17/10/2024
Research area:
Medicinal Chemistry
Research area:
Other
Research area:
Chemical Biology
Journal article
108. Reactivity Profiling for High-Yielding Ynamine-Tagged Oligonucleotide Click Chemistry Bioconjugations
Published on
10/10/2024
Research area:
Bioconjugation chemistry
Research area:
Chemical Biology
Research area:
Other
Journal article
107. Biocatalytic Synthesis of Ribonucleoside Analogues Using Nucleoside Transglycosylase-2
Published on
1/10/2024
Research area:
Medicinal Chemistry
Research area:
Modulation of RNA splicing
Research area:
Other
Research area:
Chemical probe design
Journal article
106. Gram-Scale Enzymatic Synthesis of 2ʹ-Deoxyribonucleoside Analogues Using Nucleoside Transglycosylase-2
Published on
27/8/2024
Research area:
Other
Journal article
105. A First Insight into the Developability of an Immunoglobulin G3: A Combined Computational and Experimental Approach
Published on
15/7/2024
Research area:
Bioconjugation chemistry
Research area:
Medicinal Chemistry
Journal article
104. A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles
Published on
23/5/2024
Research area:
Bioconjugation chemistry
Research area:
Medicinal Chemistry
Research area:
Chemical probe design
Journal article
103. Mechanistic Basis of the Cu(OAc)2 Catalyzed Azide-Ynamine (3 + 2) Cycloaddition Reaction
Published on
7/5/2024
Research area:
Bioconjugation chemistry
Journal article
102. Innovative, combinatorial and high-throughput approaches to degrader synthesis
Published on
10/4/2024
Research area:
Chemical probe design
Research area:
Medicinal Chemistry
Research area:
Bioconjugation chemistry
Journal article
101. 2′-19F labelling of ribose in RNAs: a tool to analyse RNA/protein interactions by NMR in physiological conditions
Published on
14/2/2024
Research area:
Other
Journal article
100. Integrated Direct-to-Biology Platform for the Nanoscale Synthesis and Biological Evaluation of PROTACs
Published on
7/11/2023
Research area:
Medicinal Chemistry
Journal article
99. Antibody-Proteolysis Targeting Chimera Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 in HER2+ Cell Lines
Published on
2/11/2023
Research area:
Bioconjugation chemistry
Research area:
Medicinal Chemistry
Journal article
98. Glutathione Mediates Control of Dual Differential Bio-orthogonal Labelling of Biomolecules
Published on
31/10/2023
Research area:
Bioconjugation chemistry
Research area:
Chemical probe design
Journal article
97. Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome
Published on
17/1/2023
Research area:
Chemical probe design
Research area:
Medicinal Chemistry
Journal article
96. Fluorous-Directed Assembly of DNA Origami Nanostructures
Published on
20/12/2022
Research area:
Bioconjugation chemistry
Research area:
Chemical probe design
Journal article
95. Surface Passivation with a Perfluoroalkane Brush Improves the Precision of Single-Molecule Measurements
Published on
28/10/2022
Research area:
Chemical probe design
Journal article
94. Oligonucleotide-Recognizing Topoisomerase Inhibitors (OTIs): Precision Gene Editors for Neurodegenerative Diseases?
Published on
29/9/2022
Research area:
Chemical probe design
Journal article
93. Biophysical characterisation of the Bcl-x pre-mRNA and binding specificity of the ellipticine derivative GQC-05: Implication for alternative splicing regulation
Published on
17/8/2022
Research area:
Chemical probe design
Journal article
92. Biosynthesis of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis
Published on
18/7/2022
Research area:
Chemical probe design
Journal article
91. A Chemo- and Regioselective Tandem [3 + 2]Heteroannulation Strategy for Carbazole Synthesis: Combining Two Mechanistically Distinct Bond-Forming Processes
Published on
18/3/2022
Research area:
Chemical probe design
Journal article
90. Direct, Late-Stage Mono-N-arylation of Pentamidine: Method Development, Mechanistic Insight, and Expedient Access to Novel Antiparastitics against Diamidine-Resistant Parasites
Published on
6/8/2021
Research area:
Chemical probe design
Journal article
89. A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications
Published on
27/5/2021
Research area:
Chemical probe design
Journal article
87. Contra-thermodynamic E → Z isomerization of cinnamamides via selective energy transfer catalysis
Published on
18/12/2020
Research area:
Chemical probe design
Journal article
88. Glasgow Early Treatment Arm Favirpiravir (GETAFIX) for adults with early stage COVID-19: A structured summary of a study protocol for a randomised controlled trial
Published on
19/11/2020
Research area:
Chemical probe design
Journal article
83. Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo Activity
Published on
1/10/2020
Research area:
Bioconjugation chemistry
Journal article
85. Identification of 2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)-N-phenylpropanamides as a novel class of potent DprE1 inhibitors
Published on
15/6/2020
Research area:
Chemical probe design
Journal article
86. Biocatalytic Alkylation Cascades: Recent Advances and Future Opportunities for Late-Stage Functionalization
Published on
27/5/2020
Research area:
Chemical probe design
Journal article
84. Two-dimensional infrared spectroscopy: an emerging analytical tool?
Published on
10/2/2020
Research area:
Chemical probe design
Journal article
80. S-Adenosyl Methionine Cofactor Modifications Enhance the Biocatalytic Repertoire of Small Molecule C-Alkylation
Published on
1/10/2019
Research area:
Modulation of RNA splicing
Journal article
81. An investigation of targeted inhibition of transcription factor activity with pyrrole imidazole polyamide (PA) in chronic myeloid leukemia (CML) blast crisis cells
Published on
15/9/2019
Research area:
Modulation of RNA splicing
Journal article
78. Splice-switching small molecules: A new therapeutic approach to modulate gene expression
Published on
1/9/2019
Research area:
Modulation of RNA splicing
Journal article
82. Molecular Construction of Sulfonamide Antisense Oligonucleotides
Published on
5/8/2019
Research area:
Transcriptional regulation
Journal article
79. Whisky tasting using a bimetallic nanoplasmonic tongue
Published on
3/7/2019
Research area:
Transcriptional regulation
Journal article
77. Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components
Published on
22/5/2019
Research area:
Bioconjugation chemistry
Journal article
76. PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase Is Inhibited by Covalent Binding
Published on
26/2/2019
Research area:
Modulation of RNA splicing
Journal article
75. Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA-Binding Polyamide Analogues
Published on
8/11/2018
Research area:
Modulation of RNA splicing
Journal article
73. A flow platform for degradation-free CuAAC bioconjugation
Published on
1/10/2018
Research area:
Transcriptional regulation
Journal article
74. Organic Semiconductor Laser Platform for the Detection of DNA by AgNP Plasmonic Enhancement
Published on
18/9/2018
Research area:
Bioconjugation chemistry
Journal article
70. Effect of oligomer length on vibrational coupling and energy relaxation in double-stranded DNA
Published on
17/8/2018
Research area:
Bioconjugation chemistry
Journal article
72. The mechanisms of a mammalian splicing enhancer
Published on
16/3/2018
Research area:
Transcriptional regulation
Journal article
69. Investigation of a minor groove-binding polyamide targeted to E2F1 transcription factor in chronic myeloid leukaemia (CML) cells
Published on
1/3/2018
Research area:
Transcriptional regulation
Journal article
71. Oxidative β-C–H sulfonylation of cyclic amines
Published on
22/1/2018
Research area:
Transcriptional regulation
Journal article
68. Structural basis of DNA duplex distortion induced by thiazole-containing hairpin polyamides
Published on
29/11/2017
Research area:
Modulation of RNA splicing
Journal article
67. Specific G-quadruplex ligands modulate the alternative splicing of Bcl-X
Published on
16/11/2017
Research area:
Modulation of RNA splicing
Book chapter
4. Minor Groove Binders as Therapeutic Agents
Published on
29/7/2017
Research area:
Transcriptional regulation
Journal article
66. Modular, Step-Efficient Palladium-Catalyzed Cross-Coupling Strategy To Access C6-Heteroaryl 2-Aminopurine Ribonucleosides
Published on
6/7/2017
Research area:
Bioconjugation chemistry
Journal article
62. A Tandem Enzymatic sp2-C-Methylation Process: Coupling in Situ S-Adenosyl-l-Methionine Formation with Methyl Transfer (ChemBioChem 11/2017)
Published on
15/5/2017
Research area:
Chemical probe design
Journal article
65. Synthetic biological approaches for RNA labelling and imaging: design principles and future opportunities
Published on
8/5/2017
Research area:
Bioconjugation chemistry
Journal article
64. Strategy for Conditional Orthogonal Sequential CuAAC Reactions Using a Protected Aromatic Ynamine
Published on
28/4/2017
Research area:
Chemical probe design
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